Ryan (from "Stray") returns and Clark has to save him from Dr. Garner of the Summerholt Research Facility. Meanwhile, Aunt Nell leaves Smallville, and Lex wants to expand the plant but runs afoul of the mayor.

Catherine Lough Haggquist, Mark Gibbon, Martin Cummins, Michael St. John Smith, Mitchell Kosterman, Robert Seckler, Ryan Kelley, Sarah-Jane Redmond, Sylvesta Stuart, William B. Davis