The investigation into the death of a woman searching for the whereabouts of her late mother's antique ring leads Goren and Eames to a physician serial killer who has cleverly concealed the murder of over two hundred of his patients.

Arthur French, C.C. Loveheart, Cheryl Freeman, Christianne Tisdale, Dennis T. Pressey, Franklin Ojeda Smith, Gary Cowling, Gio Perez, Greg Zittel, Greta Martin, Gretha Boston, J.C. Montgomery, Jim R. Coleman, Jodie Lynne McClintock, Karen Ziemba, Kate Skinner, Keisha Alfred, Kevin Tighe, Marilyn Berry, Mark Woodard, Michael Cone, Michael Deeg, Paddy Croft, Steven Petrillo, Tom Galantich, Wayne Scherzer