Alex grows closer to Jane Doe as he continues to work on her case. Helen Crawford flies into Seattle for surgery. She knows someone on the staff. Colin Marlow enters the race for Chief of Surgery. George faces more problems with Callie and Izzie. Cal... (more)lie reveals a big secret. Someone treats a WWII veteran. Also Derek treats a patient near and dear to him.

Elizabeth Reaser, Jeff Perry, Mare Winningham, Roger Rees, Shohreh Aghdashloo