Everything will be bigger in Mass Effect 3, the conclusion to Commander Shepard's epic universe-saving space trilogy. We'll check out gigantic bosses, online multiplayer, and more. A disgusting, fleshy virus consumes New York City in Prototype 2, and... (more) we'll get an early look at the action. Early Peter Molyneux creation Syndicate returns as a first-person shooter from the creators of Riddick, and we'll weigh in on the results with our review. We'll get a hands-on demo of indie platformer Vessel, in which sentient machines get a little full of themselves and wreak havoc. We'll open up the X-Play Inbox for another round of answering your viewer mail. Blair Herter catches up with Gearbox's Randy Pitchford and Epic's Rod Fergusson in Las Vegas for a special Feedback DICE 2012 edition.

Randy Pitchford, Rod Fergusson