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Masters and Johnson work to save the practice from disintegrating in the face of insurrection within the clinic. As everyone in their lives either moves on or falls away, Bill and Virginia find solace in one another. Series finale.

Beau Bridges, Betty Gilpin, Danny Jacobs, David Walton, Frances Fisher, Jaeden Lieberher, Jeremy Strong, Kelli O'Hara, Kevin Christy, Michael O'Keefe, Nick Clifford